One of the advantages of the use of full thickness ex-vivo skin is the possibility to investigate the metabolism of the subcutis.

Potential modulators of fat release can be applied either topically or in the medium, mimicking the systemic application.

Our model thus can be used for the development of anti-cellulite or fat plumping formulations

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Fat modulation

The modulation of fat quantity can be measured by assessing total lipids through infrared (IR) spectroscopy analysis.